Rep. Joe Wilson made a name for himself by yelling
"You Lie" during the middle of President Barack Obama's speech to Congress.
"If you ever start to feel too good about yourself, they have this thing called the Internet." Actress Tina Fey called out her detractors in her Golden Globe acceptance speech. (Jan. 11)
"One of the very difficult parts of the decision I made on the financial crisis was to use hardworking people's money to help prevent there to be a crisis." Former President George W. Bush (Jan. 12)
"We're going to be in the Hudson." Capt. Chesley "Sully" Sullenberger informed controllers that his plane wouldn't be landing on a runway. (Jan. 15)
"I hope Obama fails." Rush Limbaugh made headlines when he voiced his opinion about the newly elected president. (Jan. 16)
"I screwed up." President Barack Obama surprised some with his response to problems with this cabinet nomination. (Feb. 3)
"It's clearly not what my mom wanted." Olympic swimmer Michael Phelps apologized after this picture caused controversy. (Feb. 4)
"I'm sorry you couldn't be here tonight." David Letterman's reaction to his interview with guest Joaquin Phoenix. (Feb. 11)
"Um, you guys said that we, um, did this for the show." The Heene family's world began to unravel when their son spoke these words in an interview. (Where are they now?) (Oct. 15)
"'This Is It' really means this is it." Michael Jackson's words became eerily true when he announced his comeback tour. (March 5)
"If I had only followed CNBC's advice, I'd have a million dollars today. Provided I'd started with $100 million." Jon Stewart in an interview with Jim Cramer (March 12)
"Can't say no one makes money from Twitter now. The NBA does." Dallas Mavericks owner Mark Cuban tweeted about the fine he received for using Twitter to complain about refs. (March 29)
"The ones who made fun of me are now nice to me." British singing phenomenon Susan Boyle gloated a bit after her life-changing performance. (April 16)
"I need to focus my attention on being a better husband, father and person." Tiger Woods made this statement after rumors of infidelity came out following a November car crash. (Dec. 11)
"You give me a water board, Dick Cheney and one hour, and I'll have him confess to the Sharon Tate murders." Former Minnesota Gov. Jesse Ventura made this claim in a CNN interview. (May 11)
"It wasn't rape-rape." Whoopi Goldberg's comment about the Roman Polanski incident was controversial. (Sept. 27)
"Welcome to the Bill and George Show." Former President George W. Bush joined this former president on stage. (May 29)
"I screwed up my life, I screwed up my kids' lives." Nadya "Octomom" Suleman, speaking about her life with 14 children. (June 4)
"I don't know anything about cars." Edward E. Whitacre Jr. admitted this when he took over the chairman role at GM. He's now the CEO. (June 9)
"The virus is not stoppable." World Health Organization Director Margaret Chan said this when she announced that H1N1 was a pandemic. (Find the latest news.) (June 11)
(compiled by msn.com)